New Frontiers in Neuroscience

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IZ2 Stimulator & LZ48M Battery Pack

An Integrated System for Closed Loop Control

Combined with the real-time processing capabilities of our RZ Processors, the IZ2 Stimulator allows you to setup dynamic closed-loop stimulation paradigms.  Vary the stimulation waveforms based on neural activity or try to induce brain-states by playing back previously recorded neural activity or activity currently occurring in another area of the brain.  The IZ2 is available in 32, 64 and 128 channel versions. To stimulate higher currents see our IZ2H’s versions for high current mode. The IZ2 can control 128 channels at up to 50 kHz, 64 channels at up to 100 kHz, and 32 channels at a maximum 200 kHz.

 

 

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Research Applications

  • Deep brain stimulation
  • Seizure disruption
  • Spike triggered stimulation

 

 

RZ2 BioAmp Processor

Real-time processing and programmable control of PZ5 modes and digital filtering.

Passive ZIF-Clip® Headstages

Digitize at the headstage utilizing an integrated amplifier chip to yield a low noise electrode recording interface.

ACO Motorized Commutator

A motorized commutator with built-in support for both neural recording and optogenetic stimulation.

Power for Stimulation

LZ48M Battery Pack

Power for stimulation is supplied with a Li-Poly battery packs the LZ48M, capable of producing the same output voltage/current characteristics.  The LZ48M has several batteries to power both the stimulation and the IZ2 stimulator logic circuitry.

 

The IZ2 can output either a voltage or current-controlled waveform and can deliver up to 300 μA per channel.  It can generate monophasic and biphasic pulses as well as arbitrary waveforms.

 

High quality convertors provide over 80 dB of dynamic range from 30 nAmps to 300 microamps.  Converting digital waveforms into analog as part of a computer-controlled neural microstimulator system, the IZ2 delivers user-defined stimuli through multichannel electrodes.  A proven digital communication system optically isolates the electrical stimulator from the waveform generators to eliminate AC power surges and noise, ensuring superior safety and performance.

Distinctive Performance Capabilities of the IZ2M Stimulator's

The IZ2H and IZ2MH is a high current range version of the IZ2 and is available up to 64 stimulus channels and is rack mountable.

 

  • Send monophasic and biphasic pulses or arbitrary waveforms.

 

  • Stimulate on up to ten electrodes simultaneously.

 

  • Utilize over 80 dB of dynamic range from 30 nAmps to 300 microamps.

 

  • Guarantee precision PCM D/As to deliver square edged pulses and arbitrary waveforms at up to 50 kHz sampling rate with a delay of only 4 samples.

IZ2M/IZ2MH Stimulator >

IZ2 Stimulation Gizmos

Supported by Synapse for Easy Visual Configuration

The IZ2 Stimulator is used with the RZ Bioamp Processor as part of a programmable microstimulator system that delivers user-defined stimuli through multichannel electrodes.

 

SpikePac is a powerful extension Gizmo for TDT’s Synapse software suite designed specifically for researchers doing multi-channel neural recordings.  TDT recently added IZ2StimGen, a stimulation interface to our SpikePac software.

 

The all new IZ2StimGen macro implements configuration and control of the IZ2 Stimulator.  It supports monophasic or biphasic pulse train stimulation with up to four stimulus configurations.  It features an easy to use interface for stimulus design, impedance checking, and real-time stimulus presentation through the IZ2 Control in Synapse.

See all the Synapse Gizmos >

RZ5D Base Processor >

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